JOB SUMMARY

We are seeking a skilled Senior Machine Learning Scientist to join our team at the Iambic Therapeutics. In this role, you will work to design, develop, train, benchmark, and deploy one out of two of our machine learning models.

1. NeuralPLexer is a protein-ligand structure prediction model based on equivariant diffusion and related techniques.

2. Enchant is a multitask and multimodal transformer model, trained at scale on a wide variety of biomedical data.

KEY RESPONSIBILITIES

Execute the full machine learning project cycle including planning, proof of concept, deployment, and maintenance of machine learning models
Perform individual and group research in the machine learning literature
Implement, train, evaluate, and deploy large transformer models
Maintain, refactor, package, and test code related to machine learning activities
Train new employees and interns in the practice of machine learning, including implementation, execution, evaluation, and deployment
Train machine learning models on many-GPU clusters
Communicate results with internal drug discovery teams and externally at conferences

QUALIFICATIONS

Required:

A wide-ranging knowledge base in machine learning with expertise in the application of deep learning to the biology, medicine, and/or chemistry
A PhD or equivalent degree in machine learning or a computational STEM field

For the NeuralPLexer role:

Responsibility: Collaborate with teams of computational scientists, biologists, and medicinal chemists to apply machine learning to structural biology and structure-based drug design problems
Previous experience: machine learning for biomolecular structure prediction, diffusion/flow-matching/normalizing flows/neural ODEs, equivariant models, application of deep learning to the physical sciences, computational protein simulation

For the Enchant role:

Previous experience at the intersection of deep learning, python programming, and high-performance computing
Previous experience in large language or transformer model, including data preparation, training, finetuning, and evaluation

ABOUT IAMBIC THERAPEUTICS

Founded in 2019 and headquartered in San Diego, California, Iambic Therapeutics is disrupting the therapeutics landscape with its unique AI-driven drug-discovery platform. Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters with strong track records of success in delivering clinically validated therapeutics. The Iambic platform has been demonstrated to deliver high-quality, differentiated therapeutics to clinical stage with unprecedented speed and across multiple target classes and mechanisms of action. The Iambic team is advancing an internal pipeline of clinical assets to address urgent unmet patient needs. Learn more about the Iambic team, platform, and pipeline at iambic.ai.

MISSION & CORE VALUES

The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

ALSO

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life Insurance, 401K matching, and unlimited vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

Remote Scouter